Background: Protein structural alignment provides a fundamental basis for deriving principles of functional and evolutionary relationships. It is routinely used for structural cla...
During the last decade, the area of bioinformatics has produced an overwhelming amount of data, with the recently published draft of the human genome being the most prominent exam...
Quantification of selective pressures on regulatory sequences is a central question in studying the evolution of gene regulatory networks. Previous methods focus primarily on sing...
Background: Human endogenous retroviruses (HERVs) are surviving traces of ancient retrovirus infections and now reside within the human DNA. Recently HERV expression has been dete...
Merja Oja, Jaakko Peltonen, Jonas Blomberg, Samuel...
Tools for the identification of trans-membrane spans from the protein sequence are widely used in the experimental community. Computational structural biology seeks to increase the...