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» From Sequence to Biology: The Impact on Bioinformatics
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BMCBI
2006
140views more  BMCBI 2006»
13 years 7 months ago
MACSIMS : multiple alignment of complete sequences information management system
Background: In the post-genomic era, systems-level studies are being performed that seek to explain complex biological systems by integrating diverse resources from fields such as...
Julie D. Thompson, Arnaud Muller, Andrew M. Waterh...
CSB
2005
IEEE
136views Bioinformatics» more  CSB 2005»
14 years 1 months ago
An Algebraic Geometry Approach to Protein Structure Determination from NMR Data
Our paper describes the first provably-efficient algorithm for determining protein structures de novo, solely from experimental data. We show how the global nature of a certain ...
Lincong Wang, Ramgopal R. Mettu, Bruce Randall Don...
BMCBI
2008
95views more  BMCBI 2008»
13 years 7 months ago
PURE: A webserver for the prediction of domains in unassigned regions in proteins
Background: Protein domains are the structural and functional units of proteins. The ability to parse proteins into different domains is important for effective classification, un...
Chilamakuri C. S. Reddy, Khader Shameer, Bernard O...
JBI
2002
126views Bioinformatics» more  JBI 2002»
13 years 7 months ago
Characteristic attributes in cancer microarrays
Rapid advances in genome sequencing and gene expression microarray technologies are providing unprecedented opportunities to identify specific genes involved in complex biological...
Indra Neil Sarkar, Paul J. Planet, T. E. Bael, S. ...
BIOINFORMATICS
2011
13 years 2 months ago
Integrative network alignment reveals large regions of global network similarity in yeast and human
Motivation: High-throughput methods for detecting molecular interactions have produced large sets of biological network data with much more yet to come. Analogous to sequence alig...
Oleksii Kuchaiev, Natasa Przulj