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BMCBI
2010
103views more  BMCBI 2010»
13 years 7 months ago
Nonparametric methods for the analysis of single-color pathogen microarrays
Background: The analysis of oligonucleotide microarray data in pathogen surveillance and discovery is a challenging task. Target template concentration, nucleic acid integrity, an...
Omar J. Jabado, Sean Conlan, P. Lan Quan, Jeffrey ...
BMCBI
2007
106views more  BMCBI 2007»
13 years 7 months ago
Mining prokaryotic genomes for unknown amino acids: a stop-codon-based approach
Background: Selenocysteine and pyrrolysine are the 21st and 22nd amino acids, which are genetically encoded by stop codons. Since a number of microbial genomes have been completel...
Masashi Fujita, Hisaaki Mihara, Susumu Goto, Nobuy...
BMCBI
2010
118views more  BMCBI 2010»
13 years 7 months ago
Bacillus anthracis genome organization in light of whole transcriptome sequencing
Emerging knowledge of whole prokaryotic transcriptomes could validate a number of theoretical concepts introduced in the early days of genomics. What are the rules connecting gene...
Jeffrey Martin, Wenhan Zhu, Karla D. Passalacqua, ...
BMCBI
2004
83views more  BMCBI 2004»
13 years 7 months ago
VKCDB: Voltage-gated potassium channel database
Background: The family of voltage-gated potassium channels comprises a functionally diverse group of membrane proteins. They help maintain and regulate the potassium ion-based com...
Bin Li, Warren J. Gallin
BIOINFORMATICS
2008
97views more  BIOINFORMATICS 2008»
13 years 7 months ago
An integrated system for studying residue coevolution in proteins
Residue coevolution has recently emerged as an important concept, especially in the context of protein structures. While a multitude of different functions for quantifying it have...
Kevin Y. Yip, Prianka Patel, Philip M. Kim, Donald...