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BMCBI
2010
115views more  BMCBI 2010»
13 years 9 months ago
Multiconstrained gene clustering based on generalized projections
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
Jia Zeng, Shanfeng Zhu, Alan Wee-Chung Liew, Hong ...
BMCBI
2007
102views more  BMCBI 2007»
13 years 9 months ago
Identification of homologs in insignificant blast hits by exploiting extrinsic gene properties
Background: Homology is a key concept in both evolutionary biology and genomics. Detection of homology is crucial in fields like the functional annotation of protein sequences and...
Jos Boekhorst, Berend Snel
ANSS
2007
IEEE
14 years 3 months ago
Evaluating the Design of Biological Cells Using a Computer Workbench
For embedded systems as well as for biological cell systems, design is a feature that defines their identity. The assembly of different components in designs of both systems can ...
Tessa E. Pronk, Simon Polstra, Andy D. Pimentel, T...
BMCBI
2006
195views more  BMCBI 2006»
13 years 8 months ago
Hubs of knowledge: using the functional link structure in Biozon to mine for biologically significant entities
Background: Existing biological databases support a variety of queries such as keyword or definition search. However, they do not provide any measure of relevance for the instance...
Paul Shafer, Timothy Isganitis, Golan Yona
CIBB
2009
13 years 10 months ago
On the Use of Temporal Formal Logic to Model Gene Regulatory Networks
Modelling activities in molecular biology face the difficulty of prediction to link molecular knowledge with cell phenotypes. Even when the interaction graph between molecules is k...
Gilles Bernot, Jean-Paul Comet