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BMCBI
2005
124views more  BMCBI 2005»
13 years 8 months ago
Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection
Background: The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological information. The importance of integra...
David J. Reiss, Iliana Avila-Campillo, Vesteinn Th...
DNA
2009
Springer
185views Bioinformatics» more  DNA 2009»
14 years 3 months ago
NP-Completeness of the Direct Energy Barrier Problem without Pseudoknots
Knowledge of energy barriers between pairs of secondary structures for a given DNA or RNA molecule is useful, both in understanding RNA function in biological settings and in desig...
Ján Manuch, Chris Thachuk, Ladislav Stacho,...
BMCBI
2010
107views more  BMCBI 2010»
13 years 8 months ago
Detection of characteristic sub pathway network for angiogenesis based on the comprehensive pathway network
Background: Pathways in biological system often cooperate with each other to function. Changes of interactions among pathways tightly associate with alterations in the properties ...
Yezhou Huang, Shao Li
BMCBI
2006
85views more  BMCBI 2006»
13 years 8 months ago
Quality control for terms and definitions in ontologies and taxonomies
Background: Ontologies and taxonomies are among the most important computational resources for molecular biology and bioinformatics. A series of recent papers has shown that the G...
Jacob Köhler, Katherine Munn, Alexander R&uum...
ICFCA
2004
Springer
14 years 2 months ago
BLID: An Application of Logical Information Systems to Bioinformatics
BLID (Bio-Logical Intelligent Database) is a bioinformatic system designed to help biologists extract new knowledge from raw genome data by providing high-level facilities for both...
Sébastien Ferré, Ross D. King