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» From genomics to chemical genomics: new developments in KEGG
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CSB
2005
IEEE
210views Bioinformatics» more  CSB 2005»
14 years 1 months ago
Problem Solving Environment Approach to Integrating Diverse Biological Data Sources
Scientists face an ever-increasing challenge in investigating biological systems with high throughput experimental methods such as mass spectrometry and gene arrays because of the...
Eric G. Stephan, Kyle R. Klicker, Mudita Singhal, ...
BMCBI
2007
165views more  BMCBI 2007»
13 years 7 months ago
Ab initio identification of human microRNAs based on structure motifs
Background: MicroRNAs (miRNAs) are short, non-coding RNA molecules that are directly involved in post-transcriptional regulation of gene expression. The mature miRNA sequence bind...
Markus Brameier, Carsten Wiuf
BMCBI
2010
89views more  BMCBI 2010»
13 years 7 months ago
Detection of gene pathways with predictive power for breast cancer prognosis
Background: Prognosis is of critical interest in breast cancer research. Biomedical studies suggest that genomic measurements may have independent predictive power for prognosis. ...
Shuangge Ma, Michael R. Kosorok
BMCBI
2006
138views more  BMCBI 2006»
13 years 7 months ago
Determination of strongly overlapping signaling activity from microarray data
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
Ghislain Bidaut, Karsten Suhre, Jean-Michel Claver...
BMCBI
2007
156views more  BMCBI 2007»
13 years 7 months ago
Bio: : NEXUS: a Perl API for the NEXUS format for comparative biological data
Background: Evolutionary analysis provides a formal framework for comparative analysis of genomic and other data. In evolutionary analysis, observed data are treated as the termin...
Thomas Hladish, Vivek Gopalan, Chengzhi Liang, Wei...