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BMCBI
2007
183views more  BMCBI 2007»
13 years 7 months ago
Considerations in the identification of functional RNA structural elements in genomic alignments
Background: Accurate identification of novel, functional noncoding (nc) RNA features in genome sequence has proven more difficult than for exons. Current algorithms identify and s...
Tomas Babak, Benjamin J. Blencowe, Timothy R. Hugh...
BMCBI
2007
168views more  BMCBI 2007»
13 years 7 months ago
GOSim - an R-package for computation of information theoretic GO similarities between terms and gene products
Background: With the increased availability of high throughput data, such as DNA microarray data, researchers are capable of producing large amounts of biological data. During the...
Holger Fröhlich, Nora Speer, Annemarie Poustk...
BMCBI
2007
157views more  BMCBI 2007»
13 years 7 months ago
Impact of image segmentation on high-content screening data quality for SK-BR-3 cells
Background: High content screening (HCS) is a powerful method for the exploration of cellular signalling and morphology that is rapidly being adopted in cancer research. HCS uses ...
Andrew A. Hill, Peter LaPan, Yizheng Li, Steve Han...
BMCBI
2008
133views more  BMCBI 2008»
13 years 7 months ago
CORE_TF: a user-friendly interface to identify evolutionary conserved transcription factor binding sites in sets of co-regulated
Background: The identification of transcription factor binding sites is difficult since they are only a small number of nucleotides in size, resulting in large numbers of false po...
Matthew S. Hestand, Michiel van Galen, Michel P. V...
BMCBI
2007
151views more  BMCBI 2007»
13 years 7 months ago
Minimus: a fast, lightweight genome assembler
Background: Genome assemblers have grown very large and complex in response to the need for algorithms to handle the challenges of large whole-genome sequencing projects. Many of ...
Daniel D. Sommer, Arthur L. Delcher, Steven L. Sal...