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BMCBI
2008
160views more  BMCBI 2008»
13 years 9 months ago
Predicting cancer involvement of genes from heterogeneous data
Background: Systematic approaches for identifying proteins involved in different types of cancer are needed. Experimental techniques such as microarrays are being used to characte...
Ramon Aragues, Chris Sander, Baldo Oliva
BMCBI
2007
159views more  BMCBI 2007»
13 years 9 months ago
Computational genes: a tool for molecular diagnosis and therapy of aberrant mutational phenotype
Background: A finite state machine manipulating information-carrying DNA strands can be used to perform autonomous molecular-scale computations at the cellular level. Results: We ...
Israel Mark Martínez-Pérez, Gong Zha...
BMCBI
2010
135views more  BMCBI 2010»
13 years 9 months ago
Integration and visualization of systems biology data in context of the genome
Background: High-density tiling arrays and new sequencing technologies are generating rapidly increasing volumes of transcriptome and protein-DNA interaction data. Visualization a...
J. Christopher Bare, Tie Koide, David J. Reiss, Da...
BMCBI
2004
151views more  BMCBI 2004»
13 years 9 months ago
Design, implementation and evaluation of a practical pseudoknot folding algorithm based on thermodynamics
Background: The general problem of RNA secondary structure prediction under the widely used thermodynamic model is known to be NP-complete when the structures considered include a...
Jens Reeder, Robert Giegerich
POPL
2009
ACM
14 years 10 months ago
Modular code generation from synchronous block diagrams: modularity vs. code size
We study modular, automatic code generation from hierarchical block diagrams with synchronous semantics. Such diagrams are the fundamental model behind widespread tools in the emb...
Roberto Lublinerman, Christian Szegedy, Stavros Tr...