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WABI
2009
Springer
142views Bioinformatics» more  WABI 2009»
14 years 3 months ago
Back-Translation for Discovering Distant Protein Homologies
Background: Frameshift mutations in protein-coding DNA sequences produce a drastic change in the resulting protein sequence, which prevents classic protein alignment methods from ...
Marta Gîrdea, Laurent Noé, Gregory Ku...
RECOMB
2003
Springer
14 years 9 months ago
Whole-genome comparative annotation and regulatory motif discovery in multiple yeast species
In [13] we reported the genome sequences of S. paradoxus, S. mikatae and S. bayanus and compared these three yeast species to their close relative, S. cerevisiae. Genome-wide comp...
Manolis Kamvysselis, Nick Patterson, Bruce Birren,...
BMCBI
2007
145views more  BMCBI 2007»
13 years 9 months ago
Genome bioinformatic analysis of nonsynonymous SNPs
Background: Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the mos...
David F. Burke, Catherine L. Worth, Eva-Maria Prie...
BMCBI
2007
165views more  BMCBI 2007»
13 years 9 months ago
Ab initio identification of human microRNAs based on structure motifs
Background: MicroRNAs (miRNAs) are short, non-coding RNA molecules that are directly involved in post-transcriptional regulation of gene expression. The mature miRNA sequence bind...
Markus Brameier, Carsten Wiuf
WOTUG
2008
13 years 10 months ago
Communicating Haskell Processes: Composable Explicit Concurrency using Monads
Writing concurrent programs in languages that lack explicit support for concurrency can often be awkward and difficult. Haskell's monads provide a way to explicitly specify se...
Neil C. C. Brown