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BMCBI
2007
13 years 7 months ago
2007
Background: Orthology is one of the cornerstones of gene function prediction. Dividing the phylogenetic relations between genes into either orthologs or paralogs is however an ove...
BMCBI
2008
13 years 7 months ago
2008
Background: The current versions of the COG and arCOG databases, both excellent frameworks for studies in comparative and functional genomics, do not contain the nucleotide sequen...
BMCBI
2006
13 years 7 months ago
2006
Background: Measuring each protein's importance in signaling networks helps to identify the crucial proteins in a cellular process, find the fragile portion of the biology sy...
BMCBI
2010
13 years 7 months ago
2010
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
GIS
2005
ACM
14 years 8 months ago
2005
ACM
Geographic Information Systems (GIS) are increasingly managing very large sets of data and hence a centralized data repository may not always provide the most scalable solution. H...