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BMCBI
2005
169views more  BMCBI 2005»
13 years 8 months ago
Genetic interaction motif finding by expectation maximization - a novel statistical model for inferring gene modules from synthe
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...
Yan Qi 0003, Ping Ye, Joel S. Bader
IJBRA
2010
134views more  IJBRA 2010»
13 years 7 months ago
Deterministic graph-theoretic algorithm for detecting modules in biological interaction networks
—Accumulating evidence suggests that biological systems exhibit modular organization. Accurate identification of modularity is vital for understanding this organization. A recen...
Roger L. Chang, Feng Luo, Stuart Johnson, Richard ...
BMCBI
2006
94views more  BMCBI 2006»
13 years 8 months ago
Fly-DPI: database of protein interactomes for D. melanogaster in the approach of systems biology
Background: Proteins control and mediate many biological activities of cells by interacting with other protein partners. This work presents a statistical model to predict protein ...
Chung-Yen Lin, Shu-Hwa Chen, Chi-Shiang Cho, Chia-...
DILS
2009
Springer
14 years 3 months ago
Integration of Full-Coverage Probabilistic Functional Networks with Relevance to Specific Biological Processes
Probabilistic functional integrated networks are powerful tools with which to draw inferences from high-throughput data. However, network analyses are generally not tailored to spe...
Katherine James, Anil Wipat, Jennifer Hallinan
BMCBI
2008
132views more  BMCBI 2008»
13 years 8 months ago
SCOWLP classification: Structural comparison and analysis of protein binding regions
Background: Detailed information about protein interactions is critical for our understanding of the principles governing protein recognition mechanisms. The structures of many pr...
Joan Teyra, Maciej Paszkowski-Rogacz, Gerd Anders,...