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BMCBI
2007
86views more  BMCBI 2007»
13 years 9 months ago
Toxicogenomic analysis incorporating operon-transcriptional coupling and toxicant concentration-expression response: analysis of
Background: Deficiencies in microarray technology cause unwanted variation in the hybridization signal, obscuring the true measurements of intracellular transcript levels. Here we...
William O. Ward, Carol D. Swartz, Steffen Porwolli...
BMCBI
2006
106views more  BMCBI 2006»
13 years 9 months ago
Prediction of the functional class of metal-binding proteins from sequence derived physicochemical properties by support vector
Metal-binding proteins play important roles in structural stability, signaling, regulation, transport, immune response, metabolism control, and metal homeostasis. Because of their...
H. H. Lin, L. Y. Han, H. L. Zhang, C. J. Zheng, B....
BMCBI
2005
173views more  BMCBI 2005»
13 years 9 months ago
Phydbac "Gene Function Predictor" : a gene annotation tool based on genomic context analysis
Background: The large amount of completely sequenced genomes allows genomic context analysis to predict reliable functional associations between prokaryotic proteins. Major method...
François Enault, Karsten Suhre, Jean-Michel...
BMCBI
2006
85views more  BMCBI 2006»
13 years 9 months ago
Use of physiological constraints to identify quantitative design principles for gene expression in yeast adaptation to heat shoc
Background: Understanding the relationship between gene expression changes, enzyme activity shifts, and the corresponding physiological adaptive response of organisms to environme...
Ester Vilaprinyó, Rui Alves, Albert Sorriba...
BIBM
2008
IEEE
142views Bioinformatics» more  BIBM 2008»
14 years 3 months ago
Using Global Sequence Similarity to Enhance Biological Sequence Labeling
Identifying functionally important sites from biological sequences, formulated as a biological sequence labeling problem, has broad applications ranging from rational drug design ...
Cornelia Caragea, Jivko Sinapov, Drena Dobbs, Vasa...