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» Functional site prediction selects correct protein models
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BMCBI
2008
173views more  BMCBI 2008»
13 years 10 months ago
Improved machine learning method for analysis of gas phase chemistry of peptides
Background: Accurate peptide identification is important to high-throughput proteomics analyses that use mass spectrometry. Search programs compare fragmentation spectra (MS/MS) o...
Allison Gehrke, Shaojun Sun, Lukasz A. Kurgan, Nat...
BMCBI
2007
115views more  BMCBI 2007»
13 years 9 months ago
Recognizing protein-protein interfaces with empirical potentials and reduced amino acid alphabets
Background: In structural genomics, an important goal is the detection and classification of protein–protein interactions, given the structures of the interacting partners. We h...
Guillaume Launay, Raul Mendez, Shoshana J. Wodak, ...
BMCBI
2007
112views more  BMCBI 2007»
13 years 10 months ago
PFAAT version 2.0: A tool for editing, annotating, and analyzing multiple sequence alignments
Background: By virtue of their shared ancestry, homologous sequences are similar in their structure and function. Consequently, multiple sequence alignments are routinely used to ...
Daniel R. Caffrey, Paul H. Dana, Vidhya Mathur, Ma...
BMCBI
2007
133views more  BMCBI 2007»
13 years 10 months ago
MATLIGN: a motif clustering, comparison and matching tool
Background: Sequence motifs representing transcription factor binding sites (TFBS) are commonly encoded as position frequency matrices (PFM) or degenerate consensus sequences (CS)...
Matti Kankainen, Ari Löytynoja
BMCBI
2007
114views more  BMCBI 2007»
13 years 9 months ago
Gene models from ESTs (GeneModelEST): an application on the Solanum lycopersicum genome
Background: The structure annotation of a genome is based either on ab initio methodologies or on similaritiy searches versus molecules that have been already annotated. Ab initio...
Nunzio D'Agostino, Alessandra Traini, Luigi Frusci...