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» Functional topology in a network of protein interactions
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BMCBI
2006
157views more  BMCBI 2006»
13 years 7 months ago
Comparison of protein interaction networks reveals species conservation and divergence
Background: Recent progresses in high-throughput proteomics have provided us with a first chance to characterize protein interaction networks (PINs), but also raised new challenge...
Zhi Liang, Meng Xu, Maikun Teng, Liwen Niu
BMCBI
2007
168views more  BMCBI 2007»
13 years 7 months ago
Automatic extraction of gene ontology annotation and its correlation with clusters in protein networks
Background: Uncovering cellular roles of a protein is a task of tremendous importance and complexity that requires dedicated experimental work as well as often sophisticated data ...
Nikolai Daraselia, Anton Yuryev, Sergei Egorov, Il...
CANDC
2006
ACM
13 years 7 months ago
Identification of functional modules in a PPI network by clique percolation clustering
Large-scale experiments and data integration have provided the opportunity to systematically analyze and comprehensively understand the topology of biological networks and biochem...
Shi-Hua Zhang, Xue-Mei Ning, Xiang-Sun Zhang
BMCBI
2005
253views more  BMCBI 2005»
13 years 7 months ago
The Use of Edge-Betweenness Clustering to Investigate Biological Function in Protein Interaction Networks
Background: This paper describes an automated method for finding clusters of interconnected proteins in protein interaction networks and retrieving protein annotations associated ...
Ruth Dunn, Frank Dudbridge, Christopher M. Sanders...
BMCBI
2010
156views more  BMCBI 2010»
13 years 7 months ago
Protein complex prediction via verifying and reconstructing the topology of domain-domain interactions
Background: High-throughput methods for detecting protein-protein interactions enable us to obtain large interaction networks, and also allow us to computationally identify the as...
Yosuke Ozawa, Rintaro Saito, Shigeo Fujimori, Hisa...