Background: The cost efficient two-stage design is often used in genome-wide association studies (GWASs) in searching for genetic loci underlying the susceptibility for complex di...
We describe an architecture for exploring very large design spaces, for example, spaces that arise when design candidates are generated by combining components systematically from...
John R. Josephson, B. Chandrasekaran, Mark Carroll...
In this paper, we present a memetic algorithm with novel local optimizer hybridization strategy for constrained optimization. The developed MA consists of multiple cycles. In each ...
Background: The development and improvement of reliable computational methods designed to evaluate the quality of protein models is relevant in the context of protein structure re...
Paolo Mereghetti, Maria Luisa Ganadu, Elena Papale...
Background: Rapid annotation and comparisons of genomes from multiple isolates (pan-genomes) is becoming commonplace due to advances in sequencing technology. Genome annotations c...
Samuel V. Angiuoli, Julie C. Dunning Hotopp, Steve...