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BMCBI
2010
106views more  BMCBI 2010»
13 years 9 months ago
Predicting MHC class I epitopes in large datasets
Background: Experimental screening of large sets of peptides with respect to their MHC binding capabilities is still very demanding due to the large number of possible peptide seq...
Kirsten Roomp, Iris Antes, Thomas Lengauer
BMCBI
2007
195views more  BMCBI 2007»
13 years 9 months ago
NeuroTerrain - a client-server system for browsing 3D biomedical image data sets
Background: Three dimensional biomedical image sets are becoming ubiquitous, along with the canonical atlases providing the necessary spatial context for analysis. To make full us...
Carl Gustafson, William J. Bug, Jonathan Nissanov
BMCBI
2010
125views more  BMCBI 2010»
13 years 9 months ago
Asymmetric microarray data produces gene lists highly predictive of research literature on multiple cancer types
Background: Much of the public access cancer microarray data is asymmetric, belonging to datasets containing no samples from normal tissue. Asymmetric data cannot be used in stand...
Noor B. Dawany, Aydin Tozeren
BMCBI
2008
93views more  BMCBI 2008»
13 years 9 months ago
Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throug
Background: The recent emergence of high-throughput automated image acquisition technologies has forever changed how cell biologists collect and analyze data. Historically, the in...
Zheng Yin, Xiaobo Zhou, Chris Bakal, Fuhai Li, You...
BMCBI
2007
122views more  BMCBI 2007»
13 years 9 months ago
Dissecting complex transcriptional responses using pathway-level scores based on prior information
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Harmen J. Bussemaker, Lucas D. Ward, André ...