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BMCBI
2011
12 years 11 months ago
Proteinortho: Detection of (Co-)Orthologs in Large-Scale Analysis
Background: Orthology analysis is an important part of data analysis in many areas of bioinformatics such as comparative genomics and molecular phylogenetics. The ever-increasing ...
Marcus Lechner, Sven Findeiß, Lydia Steiner,...
BMCBI
2011
12 years 11 months ago
A Novel And Well-Defined Benchmarking Method For Second Generation Read Mapping
Background: Second generation sequencing technologies yield DNA sequence data at ultra high-throughput. Common to most biological applications is a mapping of the reads to an almo...
Manuel Holtgrewe, Anne-Katrin Emde, David Weese, K...
BMCBI
2007
148views more  BMCBI 2007»
13 years 7 months ago
Blast sampling for structural and functional analyses
Background: The post-genomic era is characterised by a torrent of biological information flooding the public databases. As a direct consequence, similarity searches starting with ...
Anne Friedrich, Raymond Ripp, Nicolas Garnier, Emm...
BMCBI
2008
128views more  BMCBI 2008»
13 years 7 months ago
An efficient visualization tool for the analysis of protein mutation matrices
Background: It is useful to develop a tool that would effectively describe protein mutation matrices specifically geared towards the identification of mutations that produce eithe...
Maria Pamela C. David, Carlo M. Lapid, Vincent Ric...
NAR
2008
125views more  NAR 2008»
13 years 7 months ago
Phylogeny.fr: robust phylogenetic analysis for the non-specialist
Phylogenetic analyses are central to many research areas in biology and typically involve the identification of homologous sequences, their multiple alignment, the phylogenetic re...
Alexis Dereeper, V. Guignon, G. Blanc, Stép...