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» GDB: the Human Genome Database
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PRICAI
2004
Springer
14 years 2 days ago
Computational Methods for Identification of Human microRNA Precursors
MicroRNA (miRNA), one of non-coding RNAs (ncRNAs), regulates gene expression directly by arresting the messenger RNA (mRNA) translation, which is important for identifying putative...
Jin-Wu Nam, Wha-Jin Lee, Byoung-Tak Zhang
BMCBI
2007
111views more  BMCBI 2007»
13 years 6 months ago
Novel definition files for human GeneChips based on GeneAnnot
Background: Improvements in genome sequence annotation revealed discrepancies in the original probeset/gene assignment in Affymetrix microarray and the existence of differences be...
Francesco Ferrari, Stefania Bortoluzzi, Alessandro...
BMCBI
2010
103views more  BMCBI 2010»
13 years 6 months ago
A method of predicting changes in human gene splicing induced by genetic variants in context of cis-acting elements
Background: Polymorphic variants and mutations disrupting canonical splicing isoforms are among the leading causes of human hereditary disorders. While there is a substantial evid...
Alexander G. Churbanov, Igor Vorechovsky, Chindo H...
IPPS
2005
IEEE
14 years 9 days ago
Comparison of Current BLAST Software on Nucleotide Sequences
The computational power needed for searching exponentially growing databases, such as GenBank, has increased dramatically. Three different implementations of the most widely used ...
I. Elizabeth Cha, Eric C. Rouchka
BMCBI
2008
123views more  BMCBI 2008»
13 years 6 months ago
Shape based indexing for faster search of RNA family databases
Background: Most non-coding RNA families exert their function by means of a conserved, common secondary structure. The Rfam data base contains more than five hundred structurally ...
Stefan Janssen, Jens Reeder, Robert Giegerich