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» GENOME: a rapid coalescent-based whole genome simulator
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COCOON
2005
Springer
14 years 2 months ago
Quartet-Based Phylogeny Reconstruction from Gene Orders
Abstract. Phylogenetic reconstruction from gene-rearrangement data is attracting increasing attention from biologists and computer scientists. Methods used in reconstruction includ...
Tao Liu, Jijun Tang, Bernard M. E. Moret
BMCBI
2010
118views more  BMCBI 2010»
13 years 8 months ago
Towards realistic benchmarks for multiple alignments of non-coding sequences
Background: With the continued development of new computational tools for multiple sequence alignment, it is necessary today to develop benchmarks that aid the selection of the mo...
Jaebum Kim, Saurabh Sinha
RECOMB
2007
Springer
14 years 8 months ago
An Efficient and Accurate Graph-Based Approach to Detect Population Substructure
Currently, large-scale projects are underway to perform whole genome disease association studies. Such studies involve the genotyping of hundreds of thousands of SNP markers. One o...
Srinath Sridhar, Satish Rao, Eran Halperin
BMCBI
2010
107views more  BMCBI 2010»
13 years 8 months ago
Conditional random pattern model for copy number aberration detection
Background: DNA copy number aberration (CNA) is very important in the pathogenesis of tumors and other diseases. For example, CNAs may result in suppression of anti-oncogenes and ...
Fuhai Li, Xiaobo Zhou, Wanting Huang, Chung-Che Ch...
BMCBI
2010
111views more  BMCBI 2010»
13 years 8 months ago
Functional Analysis: Evaluation of Response Intensities - Tailoring ANOVA for Lists of Expression Subsets
Background: Microarray data is frequently used to characterize the expression profile of a whole genome and to compare the characteristics of that genome under several conditions....
Fabrice Berger, Bertrand De Meulder, Anthoula Gaig...