Background: There are several situations in population biology research where simulating DNA sequences is useful. Simulation of biological populations under different evolutionary...
We study the minimum mosaic problem, an optimization problem originated in population genomics. We develop a new lower bound, called the C bound. The C bound is provably higher and...
Background: FREGENE simulates sequence-level data over large genomic regions in large populations. Because, unlike coalescent simulators, it works forwards through time, it allows...
Marc Chadeau-Hyam, Clive J. Hoggart, Paul F. O'Rei...
Background: Using microarray and sequencing platforms, a large number of copy number variations (CNVs) have been identified in humans. In practice, because our human genome is a d...
The next phase of human genomics will involve largescale screens of populations for signi cant DNA polymorphisms, notably single nucleotide polymorphisms SNP's. Dense human S...