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» GPX: Interactive Mining of Gene Expression Data
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BMCBI
2008
116views more  BMCBI 2008»
13 years 7 months ago
The combination approach of SVM and ECOC for powerful identification and classification of transcription factor
Background: Transcription factors (TFs) are core functional proteins which play important roles in gene expression control, and they are key factors for gene regulation network co...
Guangyong Zheng, Ziliang Qian, Qing Yang, Chaochun...
ICDM
2008
IEEE
146views Data Mining» more  ICDM 2008»
14 years 1 months ago
Hunting for Coherent Co-clusters in High Dimensional and Noisy Datasets
Clustering problems often involve datasets where only a part of the data is relevant to the problem, e.g., in microarray data analysis only a subset of the genes show cohesive exp...
Meghana Deodhar, Joydeep Ghosh, Gunjan Gupta, Hyuk...
BMCBI
2007
154views more  BMCBI 2007»
13 years 7 months ago
Inferring biological networks with output kernel trees
Background: Elucidating biological networks between proteins appears nowadays as one of the most important challenges in systems biology. Computational approaches to this problem ...
Pierre Geurts, Nizar Touleimat, Marie Dutreix, Flo...
BMCBI
2006
108views more  BMCBI 2006»
13 years 7 months ago
Probe set algorithms: is there a rational best bet?
Affymetrix microarrays have become a standard experimental platform for studies of mRNA expression profiling. Their success is due, in part, to the multiple oligonucleotide featur...
Jinwook Seo, Eric P. Hoffman
BMCBI
2006
115views more  BMCBI 2006»
13 years 7 months ago
SimArray: a user-friendly and user-configurable microarray design tool
Background: Microarrays were first developed to assess gene expression but are now also used to map protein-binding sites and to assess allelic variation between individuals. Rega...
Richard P. Auburn, Roslin R. Russell, Bettina Fisc...