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BMCBI
2010
155views more  BMCBI 2010»
13 years 8 months ago
BrEPS: a flexible and automatic protocol to compute enzyme-specific sequence profiles for functional annotation
Background: Models for the simulation of metabolic networks require the accurate prediction of enzyme function. Based on a genomic sequence, enzymatic functions of gene products a...
Constantin Bannert, A. Welfle, C. aus dem Spring, ...
MEDES
2010
ACM
13 years 5 months ago
Brazilian public software: beyond sharing
This work presents a case of an innovative Brazilian experience of use of free software in public administration as an emergent ecosystem, and the attempt to establish a quality f...
A. M. Alves, Marcelo Schneck de Paula Pessôa
BMCBI
2011
13 years 2 months ago
Detection of Lineage-Specific Evolutionary Changes among Primate Species
Background: Comparison of the human genome with other primates offers the opportunity to detect evolutionary events that created the diverse phenotypes among the primate species. ...
Mihaela Pertea, Geo Pertea, Steven L. Salzberg
IJPP
2011
115views more  IJPP 2011»
13 years 2 months ago
Milepost GCC: Machine Learning Enabled Self-tuning Compiler
Tuning compiler optimizations for rapidly evolving hardware makes porting and extending an optimizing compiler for each new platform extremely challenging. Iterative optimization i...
Grigori Fursin, Yuriy Kashnikov, Abdul Wahid Memon...
BMCBI
2007
127views more  BMCBI 2007»
13 years 11 months ago
Predicting the phenotypic effects of non-synonymous single nucleotide polymorphisms based on support vector machines
Background: Human genetic variations primarily result from single nucleotide polymorphisms (SNPs) that occur approximately every 1000 bases in the overall human population. The no...
Jian Tian, Ningfeng Wu, Xuexia Guo, Jun Guo, Juhua...