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BMCBI
2008
122views more  BMCBI 2008»
13 years 8 months ago
OpenDMAP: An open source, ontology-driven concept analysis engine, with applications to capturing knowledge regarding protein tr
Background: Information extraction (IE) efforts are widely acknowledged to be important in harnessing the rapid advance of biomedical knowledge, particularly in areas where import...
Lawrence Hunter, Zhiyong Lu, James Firby, William ...
BMCBI
2010
181views more  BMCBI 2010»
13 years 8 months ago
Intensity dependent estimation of noise in microarrays improves detection of differentially expressed genes
Background: In many microarray experiments, analysis is severely hindered by a major difficulty: the small number of samples for which expression data has been measured. When one ...
Amit Zeisel, Amnon Amir, Wolfgang J. Köstler,...
BMCBI
2010
178views more  BMCBI 2010»
13 years 8 months ago
Selecting high-dimensional mixed graphical models using minimal AIC or BIC forests
Background: Chow and Liu showed that the maximum likelihood tree for multivariate discrete distributions may be found using a maximum weight spanning tree algorithm, for example K...
David Edwards, Gabriel C. G. de Abreu, Rodrigo Lab...
BMCBI
2010
91views more  BMCBI 2010»
13 years 6 months ago
Washing scaling of GeneChip microarray expression
Background: Post-hybridization washing is an essential part of microarray experiments. Both the quality of the experimental washing protocol and adequate consideration of washing ...
Hans Binder, Knut Krohn, Conrad J. Burden
RECOMB
2002
Springer
14 years 8 months ago
Phase-independent rhythmic analysis of genome-wide expression patterns
We introduce a model-based analysis technique for extracting and characterizing rhythmic expression pro les from genome-wide DNA microarray hybridization data. These patterns are ...
Christopher James Langmead, Anthony K. Yan, C. Rob...