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BMCBI
2007
207views more  BMCBI 2007»
13 years 8 months ago
Analyzing in situ gene expression in the mouse brain with image registration, feature extraction and block clustering
Background: Many important high throughput projects use in situ hybridization and may require the analysis of images of spatial cross sections of organisms taken with cellular lev...
Manjunatha Jagalur, Chris Pal, Erik G. Learned-Mil...
BMEI
2008
IEEE
13 years 10 months ago
Clustering of High-Dimensional Gene Expression Data with Feature Filtering Methods and Diffusion Maps
The importance of gene expression data in cancer diagnosis and treatment by now has been widely recognized by cancer researchers in recent years. However, one of the major challen...
Rui Xu, Steven Damelin, Boaz Nadler, Donald C. Wun...
BMCBI
2006
156views more  BMCBI 2006»
13 years 8 months ago
Score-based prediction of genomic islands in prokaryotic genomes using hidden Markov models
Background: Horizontal gene transfer (HGT) is considered a strong evolutionary force shaping the content of microbial genomes in a substantial manner. It is the difference in spee...
Stephan Waack, Oliver Keller, Roman Asper, Thomas ...
BMCBI
2007
147views more  BMCBI 2007»
13 years 8 months ago
Statistical analysis and significance testing of serial analysis of gene expression data using a Poisson mixture model
Background: Serial analysis of gene expression (SAGE) is used to obtain quantitative snapshots of the transcriptome. These profiles are count-based and are assumed to follow a Bin...
Scott D. Zuyderduyn
BMCBI
2006
147views more  BMCBI 2006»
13 years 8 months ago
A hidden Markov model approach for determining expression from genomic tiling micro arrays
Background: Genomic tiling micro arrays have great potential for identifying previously undiscovered coding as well as non-coding transcription. To-date, however, analyses of thes...
Kasper Munch, Paul P. Gardner, Peter Arctander, An...