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» Gene Expression Clustering with Functional Mixture Models
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ICAI
2007
13 years 11 months ago
Mining and Dynamic Simulation of Sub-Networks from Large Biomolecular Networks
Biomolecular networks dynamically respond to stimuli and implement cellular function. Understanding these dynamic changes is the key challenge for cell biologists. As biomolecular...
Xiaohua Hu, Fang-Xiang Wu, Michael K. Ng, Bahrad A...
GECCO
2004
Springer
143views Optimization» more  GECCO 2004»
14 years 3 months ago
Efficient Clustering-Based Genetic Algorithms in Chemical Kinetic Modelling
Two efficient clustering-based genetic algorithms are developed for the optimisation of reaction rate parameters in chemical kinetic modelling. The genetic algorithms employed are ...
Lionel Elliott, Derek B. Ingham, Adrian G. Kyne, N...
NN
2007
Springer
267views Neural Networks» more  NN 2007»
13 years 9 months ago
Modeling of gene regulatory networks with hybrid differential evolution and particle swarm optimization
In the last decade, recurrent neural networks (RNNs) have attracted more efforts in inferring genetic regulatory networks (GRNs), using time series gene expression data from micro...
Rui Xu, Ganesh K. Venayagamoorthy, Donald C. Wunsc...
CSB
2003
IEEE
130views Bioinformatics» more  CSB 2003»
14 years 3 months ago
A Computational Approach to Reconstructing Gene Regulatory Networks
Reverse-engineering of gene networks using linear models often results in an underdetermined system because of excessive unknown parameters. In addition, the practical utility of ...
Xutao Deng, Hesham H. Ali
JCST
2008
124views more  JCST 2008»
13 years 10 months ago
Clustering by Pattern Similarity
The task of clustering is to identify classes of similar objects among a set of objects. The definition of similarity varies from one clustering model to another. However, in most ...
Haixun Wang, Jian Pei