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CSB
2005
IEEE
165views Bioinformatics» more  CSB 2005»
13 years 9 months ago
Sequential Diagonal Linear Discriminant Analysis (SeqDLDA) for Microarray Classification and Gene Identification
In microarray classification we are faced with a very large number of features and very few training samples. This is a challenge for classical Linear Discriminant Analysis (LDA),...
Roger Pique-Regi, Antonio Ortega, Shahab Asgharzad...
BIBM
2009
IEEE
172views Bioinformatics» more  BIBM 2009»
14 years 15 days ago
Identifying Gene Signatures from Cancer Progression Data Using Ordinal Analysis
—A comprehensive understanding of cancer progression may shed light on genetic and molecular mechanisms of oncogenesis, and it may provide much needed information for effective d...
Yoon Soo Pyon, Jing Li
BMCBI
2007
112views more  BMCBI 2007»
13 years 7 months ago
Selecting dissimilar genes for multi-class classification, an application in cancer subtyping
Background: Gene expression microarray is a powerful technology for genetic profiling diseases and their associated treatments. Such a process involves a key step of biomarker ide...
Zhipeng Cai, Randy Goebel, Mohammad R. Salavatipou...
BMCBI
2006
155views more  BMCBI 2006»
13 years 7 months ago
Analysis of promoter regions of co-expressed genes identified by microarray analysis
Background: The use of global gene expression profiling to identify sets of genes with similar expression patterns is rapidly becoming a widespread approach for understanding biol...
Srinivas Veerla, Mattias Höglund
BIBM
2009
IEEE
155views Bioinformatics» more  BIBM 2009»
14 years 2 months ago
Towards Reliable Isoform Quantification Using RNA-Seq Data
Background: In eukaryotes, alternative splicing often generates multiple splice variants from a single gene. Here weexplore the use of RNA sequencing (RNA-Seq) datasets to address...
Brian E. Howard, Steffen Heber