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BMCBI
2011
13 years 2 months ago
Identifying hypermethylated CpG islands using a quantile regression model
Background: DNA methylation has been shown to play an important role in the silencing of tumor suppressor genes in various tumor types. In order to have a system-wide understandin...
Shuying Sun, Zhengyi Chen, Pearlly Yan, Yi-Wen Hua...
BMCBI
2008
133views more  BMCBI 2008»
13 years 7 months ago
A Web-based and Grid-enabled dChip version for the analysis of large sets of gene expression data
Background: Microarray techniques are one of the main methods used to investigate thousands of gene expression profiles for enlightening complex biological processes responsible f...
Luca Corradi, Marco Fato, Ivan Porro, Silvia Scagl...
BMCBI
2010
110views more  BMCBI 2010»
13 years 7 months ago
TimeDelay-ARACNE: Reverse engineering of gene networks from time-course data by an information theoretic approach
Background: One of main aims of Molecular Biology is the gain of knowledge about how molecular components interact each other and to understand gene function regulations. Using mi...
Pietro Zoppoli, Sandro Morganella, Michele Ceccare...
BMCBI
2006
102views more  BMCBI 2006»
13 years 7 months ago
Microarray analysis distinguishes differential gene expression patterns from large and small colony Thymidine kinase mutants of
Background: The Thymidine kinase (Tk) mutants generated from the widely used L5178Y mouse lymphoma assay fall into two categories, small colony and large colony. Cells from the la...
Tao Han, Jianyong Wang, Weida Tong, Martha M. Moor...
BIBE
2007
IEEE
153views Bioinformatics» more  BIBE 2007»
13 years 9 months ago
Combined expression data with missing values and gene interaction network analysis: a Markovian integrated approach
—DNA microarray technologies provide means for monitoring in the order of tens of thousands of gene expression levels quantitatively and simultaneously. However data generated in...
Juliette Blanchet, Matthieu Vignes