The last decade has witnessed an exponential growth of sequence information in the field of biological macromolecules such as proteins and nucleic acids and their interactions wit...
Sandhya Shenoy, B. Jayaram, N. Latha, Pooja Narang...
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
Background: Understanding how genes are expressed and regulated in different tissues is a fundamental and challenging question. However, most of currently available biological dat...
Xiong Liu, Xueping Yu, Donald J. Zack, Heng Zhu, J...
Background: Protein-coding gene detection in prokaryotic genomes is considered a much simpler problem than in intron-containing eukaryotic genomes. However there have been reports...
Andrew S. Warren, Jeremy S. Archuleta, Wu-chun Fen...
Background: Computational methods to predict transcription factor binding sites (TFBS) based on exhaustive algorithms are guaranteed to find the best patterns but are often limite...