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» Gene Specific Co-regulation Discovery: An Improved Approach
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CEC
2007
IEEE
13 years 11 months ago
Gene selection in cancer classification using PSO/SVM and GA/SVM hybrid algorithms
In this work we compare the use of a Particle Swarm Optimization (PSO) and a Genetic Algorithm (GA) (both augmented with Support Vector Machines SVM) for the classification of high...
Enrique Alba, José García-Nieto, Lae...
BMCBI
2007
226views more  BMCBI 2007»
13 years 7 months ago
MiRFinder: an improved approach and software implementation for genome-wide fast microRNA precursor scans
Background: MicroRNAs (miRNAs) are recognized as one of the most important families of noncoding RNAs that serve as important sequence-specific post-transcriptional regulators of ...
Ting-Hua Huang, Bin Fan, Max F. Rothschild, Zhi-Li...
BMCBI
2008
107views more  BMCBI 2008»
13 years 7 months ago
A mixture model approach to sample size estimation in two-sample comparative microarray experiments
Background: Choosing the appropriate sample size is an important step in the design of a microarray experiment, and recently methods have been proposed that estimate sample sizes ...
Tommy S. Jørstad, Herman Midelfart, Atle M....
BMCBI
2008
142views more  BMCBI 2008»
13 years 7 months ago
Microarray data mining: A novel optimization-based approach to uncover biologically coherent structures
Background: DNA microarray technology allows for the measurement of genome-wide expression patterns. Within the resultant mass of data lies the problem of analyzing and presenting...
Meng Piao Tan, Erin N. Smith, James R. Broach, Chr...
BMCBI
2008
167views more  BMCBI 2008»
13 years 7 months ago
Not proper ROC curves as new tool for the analysis of differentially expressed genes in microarray experiments
Background: Most microarray experiments are carried out with the purpose of identifying genes whose expression varies in relation with specific conditions or in response to enviro...
Stefano Parodi, Vito Pistoia, Marco Muselli