128 search results - page 13 / 26 » Gene Specific Co-regulation Discovery: An Improved Approach |
BIOCOMP
2008
13 years 9 months ago
2008
-- To successfully apply RNAi, the very first step is to design functional siRNA or shRNA sequences targeting specific genes. Many characteristics of functional synthetic siRNAs ha...
BMCBI
2007
13 years 7 months ago
2007
Background: Nowadays modern biology aims at unravelling the strands of complex biological structures such as the protein-protein interaction (PPI) networks. A key concept in the o...
BMCBI
2006
13 years 7 months ago
2006
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
BMCBI
2006
13 years 7 months ago
2006
Background: In class prediction problems using microarray data, gene selection is essential to improve the prediction accuracy and to identify potential marker genes for a disease...
BMCBI
2008
13 years 7 months ago
2008
Background: Computational discovery of motifs in biomolecular sequences is an established field, with applications both in the discovery of functional sites in proteins and regula...