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» Gene finding in novel genomes
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BMCBI
2006
160views more  BMCBI 2006»
13 years 8 months ago
Gene prediction in eukaryotes with a generalized hidden Markov model that uses hints from external sources
Background: In order to improve gene prediction, extrinsic evidence on the gene structure can be collected from various sources of information such as genome-genome comparisons an...
Mario Stanke, Oliver Schöffmann, Burkhard Mor...
BMCBI
2005
87views more  BMCBI 2005»
13 years 8 months ago
Efficient decoding algorithms for generalized hidden Markov model gene finders
Background: The Generalized Hidden Markov Model (GHMM) has proven a useful framework for the task of computational gene prediction in eukaryotic genomes, due to its flexibility an...
William H. Majoros, Mihaela Pertea, Arthur L. Delc...
BMCBI
2007
162views more  BMCBI 2007»
13 years 8 months ago
Genome-wide identification of specific oligonucleotides using artificial neural network and computational genomic analysis
Background: Genome-wide identification of specific oligonucleotides (oligos) is a computationallyintensive task and is a requirement for designing microarray probes, primers, and ...
Chun-Chi Liu, Chin-Chung Lin, Ker-Chau Li, Wen-Shy...
GG
2004
Springer
14 years 1 months ago
Tutorial on DNA Computing and Graph Transformation
that graph transformations provide the right level of abstraction, and useful technical tools for studying gene assembly. On the other hand, the gene assembly process inspires a ne...
Tero Harju, Ion Petre, Grzegorz Rozenberg
BMCBI
2008
151views more  BMCBI 2008»
13 years 8 months ago
An integrated database-pipeline system for studying single nucleotide polymorphisms and diseases
Background: Studies on the relationship between disease and genetic variations such as single nucleotide polymorphisms (SNPs) are important. Genetic variations can cause disease b...
Jin Ok Yang, Sohyun Hwang, Jeongsu Oh, Jong Bhak, ...