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» Gene finding in novel genomes
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BMCBI
2008
143views more  BMCBI 2008»
13 years 8 months ago
Gene identification and protein classification in microbial metagenomic sequence data via incremental clustering
Background: The identification and study of proteins from metagenomic datasets can shed light on the roles and interactions of the source organisms in their communities. However, ...
Shibu Yooseph, Weizhong Li, Granger G. Sutton
BIBM
2010
IEEE
161views Bioinformatics» more  BIBM 2010»
13 years 6 months ago
Cis-regulatory module detection using constraint programming
We propose a method for finding CRMs in a set of co-regulated genes. Each CRM consists of a set of binding sites of transcription factors. We wish to find CRMs involving the same t...
Tias Guns, Hong Sun, Kathleen Marchal, Siegfried N...
BMCBI
2005
178views more  BMCBI 2005»
13 years 8 months ago
A quantization method based on threshold optimization for microarray short time series
Background: Reconstructing regulatory networks from gene expression profiles is a challenging problem of functional genomics. In microarray studies the number of samples is often ...
Barbara Di Camillo, Fatima Sanchez-Cabo, Gianna To...
RECOMB
2006
Springer
14 years 8 months ago
Structural Alignment of Pseudoknotted RNA
In this paper, we address the problem of discovering novel non-coding RNA (ncRNA) using primary sequence, and secondary structure conservation, focusing on ncRNA families with pseu...
Banu Dost, Buhm Han, Shaojie Zhang, Vineet Bafna
IANDC
2011
148views more  IANDC 2011»
13 years 3 months ago
Building species trees from larger parts of phylogenomic databases
Abstract. Gene trees are leaf-labeled trees inferred from molecular sequences. Due to duplication events arising in genome evolution, gene trees usually have multiple copies of som...
Celine Scornavacca, Vincent Berry, Vincent Ranwez