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» Gene finding in novel genomes
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BMCBI
2007
162views more  BMCBI 2007»
13 years 8 months ago
Three-Dimensional Phylogeny Explorer: Distinguishing paralogs, lateral transfer, and violation of "molecular clock" assumption w
Background: Construction and interpretation of phylogenetic trees has been a major research topic for understanding the evolution of genes. Increases in sequence data and complexi...
Namshin Kim, Christopher Lee
KDD
2001
ACM
142views Data Mining» more  KDD 2001»
14 years 8 months ago
TreeDT: gene mapping by tree disequilibrium test
We introduce and evaluate TreeDT, a novel gene mapping method which is based on discovering and assessing tree-like patterns in genetic marker data. Gene mapping aims at discoveri...
Petteri Sevon, Hannu Toivonen, Vesa Ollikainen
BMCBI
2006
143views more  BMCBI 2006»
13 years 8 months ago
Discovering functional gene expression patterns in the metabolic network of Escherichia coli with wavelets transforms
Background: Microarray technology produces gene expression data on a genomic scale for an endless variety of organisms and conditions. However, this vast amount of information nee...
Rainer König, Gunnar Schramm, Marcus Oswald, ...
KDD
2009
ACM
249views Data Mining» more  KDD 2009»
14 years 8 months ago
Drosophila gene expression pattern annotation using sparse features and term-term interactions
The Drosophila gene expression pattern images document the spatial and temporal dynamics of gene expression and they are valuable tools for explicating the gene functions, interac...
Shuiwang Ji, Lei Yuan, Ying-Xin Li, Zhi-Hua Zhou, ...
BMCBI
2007
102views more  BMCBI 2007»
13 years 8 months ago
Multivariate Analysis and Visualization of Splicing Correlations in Single-Gene Transcriptomes
Background: RNA metabolism, through 'combinatorial splicing', can generate enormous structural diversity in the proteome. Alternative domains may interact, however, with...
Mark C. Emerick, Giovanni Parmigiani, William S. A...