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» Gene finding in novel genomes
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BMCBI
2002
134views more  BMCBI 2002»
13 years 7 months ago
CoreGenes: A computational tool for identifying and cataloging "core" genes in a set of small genomes
Background: Improvements in DNA sequencing technology and methodology have led to the rapid expansion of databases comprising DNA sequence, gene and genome data. Lower operational...
Nikhat Zafar, Raja Mazumder, Donald Seto
BMCBI
2006
122views more  BMCBI 2006»
13 years 8 months ago
Computational reconstruction of transcriptional regulatory modules of the yeast cell cycle
Background: A transcriptional regulatory module (TRM) is a set of genes that is regulated by a common set of transcription factors (TFs). By organizing the genome into TRMs, a liv...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
BMCBI
2008
105views more  BMCBI 2008»
13 years 8 months ago
SIGMA2: A system for the integrative genomic multi-dimensional analysis of cancer genomes, epigenomes, and transcriptomes
Background: High throughput microarray technologies have afforded the investigation of genomes, epigenomes, and transcriptomes at unprecedented resolution. However, software packa...
Raj Chari, Bradley P. Coe, Craig Wedseltoft, Marie...
BMCBI
2008
110views more  BMCBI 2008»
13 years 8 months ago
Finding microRNA regulatory modules in human genome using rule induction
Background: MicroRNAs (miRNAs) are a class of small non-coding RNA molecules (20
Dang Hung Tran, Kenji Satou, Tu Bao Ho
BMCBI
2008
126views more  BMCBI 2008»
13 years 8 months ago
c-REDUCE: Incorporating sequence conservation to detect motifs that correlate with expression
Background: Computational methods for characterizing novel transcription factor binding sites search for sequence patterns or "motifs" that appear repeatedly in genomic ...
Katerina Kechris, Hao Li