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» Gene finding in novel genomes
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RECOMB
2008
Springer
14 years 8 months ago
Accurate Computation of Likelihoods in the Coalescent with Recombination Via Parsimony
Understanding the variation of recombination rates across a given genome is crucial for disease gene mapping and for detecting signatures of selection, to name just a couple of app...
Jotun Hein, Rune B. Lyngsø, Yun S. Song
BMCBI
2006
110views more  BMCBI 2006»
13 years 8 months ago
CpGcluster: a distance-based algorithm for CpG-island detection
Background: Despite their involvement in the regulation of gene expression and their importance as genomic markers for promoter prediction, no objective standard exists for defini...
Michael Hackenberg, Christopher Previti, Pedro Lui...
BMCBI
2010
112views more  BMCBI 2010»
13 years 8 months ago
Computational identification of rare codons of Escherichia coli based on codon pairs preference
Background: Codon bias is believed to play an important role in the control of gene expression. In Escherichia coli, some rare codons, which can limit the expression level of exog...
Xianming Wu, Songfeng Wu, Dong Li, Jiyang Zhang, L...
BMCBI
2008
114views more  BMCBI 2008»
13 years 8 months ago
Identifying a few foot-and-mouth disease virus signature nucleotide strings for computational genotyping
Background: Serotypes of the Foot-and-Mouth disease viruses (FMDVs) were generally determined by biological experiments. The computational genotyping is not well studied even with...
Guohui Lin, Zhipeng Cai, Junfeng Wu, Xiu-Feng Wan,...
BMCBI
2007
111views more  BMCBI 2007»
13 years 8 months ago
Modular co-evolution of metabolic networks
Background: The architecture of biological networks has been reported to exhibit high level of modularity, and to some extent, topological modules of networks overlap with known f...
Jing Zhao, Guohui Ding, Lin Tao, Hong Yu, Zhong-Ha...