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» Gene finding in novel genomes
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BMCBI
2006
153views more  BMCBI 2006»
13 years 8 months ago
The 3of5 web application for complex and comprehensive pattern matching in protein sequences
Background: The identification of patterns in biological sequences is a key challenge in genome analysis and in proteomics. Frequently such patterns are complex and highly variabl...
Markus Seiler, Alexander Mehrle, Annemarie Poustka...
BMCBI
2005
120views more  BMCBI 2005»
13 years 7 months ago
Harshlight: a "corrective make-up" program for microarray chips
Background: Microscopists are familiar with many blemishes that fluorescence images can have due to dust and debris, glass flaws, uneven distribution of fluids or surface coatings...
Mayte Suárez-Fariñas, Maurizio Pelle...
RECOMB
2004
Springer
14 years 8 months ago
Mining protein family specific residue packing patterns from protein structure graphs
Finding recurring residue packing patterns, or spatial motifs, that characterize protein structural families is an important problem in bioinformatics. To this end, we apply a nov...
Jun Huan, Wei Wang 0010, Deepak Bandyopadhyay, Jac...
BMCBI
2008
162views more  BMCBI 2008»
13 years 8 months ago
Improved identification of conserved cassette exons using Bayesian networks
Background: Alternative splicing is a major contributor to the diversity of eukaryotic transcriptomes and proteomes. Currently, large scale detection of alternative splicing using...
Rileen Sinha, Michael Hiller, Rainer Pudimat, Ulri...
BMCBI
2005
61views more  BMCBI 2005»
13 years 7 months ago
Proteins with two SUMO-like domains in chromatin-associated complexes: The RENi (Rad60-Esc2-NIP45) family
Background: Post-translational modification by Small Ubiquitin-like Modifiers (SUMO) has been implicated in protein targeting, in the maintenance of genomic integrity and in trans...
Maria Novatchkova, Andreas Bachmair, Birgit Eisenh...