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BMCBI
2007
94views more  BMCBI 2007»
13 years 7 months ago
False positive reduction in protein-protein interaction predictions using gene ontology annotations
Background: Many crucial cellular operations such as metabolism, signalling, and regulations are based on protein-protein interactions. However, the lack of robust protein-protein...
Mahmood A. Mahdavi, Yen-Han Lin
BMCBI
2008
141views more  BMCBI 2008»
13 years 7 months ago
The development of PIPA: an integrated and automated pipeline for genome-wide protein function annotation
Background: Automated protein function prediction methods are needed to keep pace with high-throughput sequencing. With the existence of many programs and databases for inferring ...
Chenggang Yu, Nela Zavaljevski, Valmik Desai, Seth...
NAR
2006
91views more  NAR 2006»
13 years 7 months ago
YOGY: a web-based, integrated database to retrieve protein orthologs and associated Gene Ontology terms
We present YOGY a web-based resource for orthologous proteins from nine eukaryotic organisms: Homo sapiens, Mus musculus, Rattus norvegicus, Arabidopsis thaliana, Drosophila melan...
Christopher J. Penkett, James A. Morris, Valerie W...
BMCBI
2005
198views more  BMCBI 2005»
13 years 7 months ago
Clustering protein sequences with a novel metric transformed from sequence similarity scores and sequence alignments with neural
Background: The sequencing of the human genome has enabled us to access a comprehensive list of genes (both experimental and predicted) for further analysis. While a majority of t...
Qicheng Ma, Gung-Wei Chirn, Richard Cai, Joseph D....
TCBB
2010
106views more  TCBB 2010»
13 years 5 months ago
Predicting Novel Human Gene Ontology Annotations Using Semantic Analysis
—The correct interpretation of many molecular biology experiments depends in an essential way on the accuracy and consistency of the existing annotation databases. Such databases...
Bogdan Done, Purvesh Khatri, Arina Done, Sorin Dra...