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» Gene functional classification from heterogeneous data
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108
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BMCBI
2006
86views more  BMCBI 2006»
15 years 3 months ago
The impact of sample imbalance on identifying differentially expressed genes
Background: Recently several statistical methods have been proposed to identify genes with differential expression between two conditions. However, very few studies consider the p...
Kun Yang, Jianzhong Li, Hong Gao
BMCBI
2005
107views more  BMCBI 2005»
15 years 3 months ago
A stepwise framework for the normalization of array CGH data
Background: In two-channel competitive genomic hybridization microarray experiments, the ratio of the two fluorescent signal intensities at each spot on the microarray is commonly...
Mehrnoush Khojasteh, Wan L. Lam, Rabab Kreidieh Wa...
155
Voted
BMCBI
2007
114views more  BMCBI 2007»
15 years 3 months ago
Mining and state-space modeling and verification of sub-networks from large-scale biomolecular networks
Background: Biomolecular networks dynamically respond to stimuli and implement cellular function. Understanding these dynamic changes is the key challenge for cell biologists. As ...
Xiaohua Hu, Fang-Xiang Wu
JCB
2002
70views more  JCB 2002»
15 years 3 months ago
Strong Feature Sets from Small Samples
For small samples, classi er design algorithms typically suffer from over tting. Given a set of features, a classi er must be designed and its error estimated. For small samples, ...
Seungchan Kim, Edward R. Dougherty, Junior Barrera...
148
Voted
BMCBI
2008
158views more  BMCBI 2008»
15 years 3 months ago
Discovering gene annotations in biomedical text databases
Currently, most of the discovered biological and biomedical knowledge is available as textual data in scientific papers. And, locating and curating information about a genomic enti...
Ali Cakmak, Gultekin Özsoyoglu