Sciweavers

1148 search results - page 35 / 230
» Gene functional classification from heterogeneous data
Sort
View
BMCBI
2010
115views more  BMCBI 2010»
13 years 10 months ago
Multiconstrained gene clustering based on generalized projections
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
Jia Zeng, Shanfeng Zhu, Alan Wee-Chung Liew, Hong ...
CSB
2004
IEEE
106views Bioinformatics» more  CSB 2004»
14 years 1 months ago
A Theoretical Analysis of Gene Selection
A great deal of recent research has focused on the challenging task of selecting differentially expressed genes from microarray data (`gene selection'). Numerous gene selecti...
Sach Mukherjee, Stephen J. Roberts
RECOMB
2010
Springer
13 years 11 months ago
Algorithms for Detecting Significantly Mutated Pathways in Cancer
Abstract. Recent genome sequencing studies have shown that the somatic mutations that drive cancer development are distributed across a large number of genes. This mutational heter...
Fabio Vandin, Eli Upfal, Benjamin J. Raphael
JCB
2007
130views more  JCB 2007»
13 years 9 months ago
Bayesian Inference of MicroRNA Targets from Sequence and Expression Data
MicroRNAs (miRNAs) regulate a large proportion of mammalian genes by hybridizing to targeted messenger RNAs (mRNAs) and down-regulating their translation into protein. Although mu...
Jim C. Huang, Quaid Morris, Brendan J. Frey
BMCBI
2004
146views more  BMCBI 2004»
13 years 9 months ago
Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
Feng Gao, Barrett C. Foat, Harmen J. Bussemaker