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» Gene functional classification from heterogeneous data
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BMCBI
2005
113views more  BMCBI 2005»
13 years 11 months ago
Systematic survey reveals general applicability of "guilt-by-association" within gene coexpression networks
Background: Biological processes are carried out by coordinated modules of interacting molecules. As clustering methods demonstrate that genes with similar expression display incr...
Cecily J. Wolfe, Isaac S. Kohane, Atul J. Butte
BMCBI
2010
96views more  BMCBI 2010»
13 years 11 months ago
QTLminer: identifying genes regulating quantitative traits
Background: Quantitative trait locus (QTL) mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to...
Rudi Alberts, Klaus Schughart
ICML
2006
IEEE
14 years 12 months ago
Learning a kernel function for classification with small training samples
When given a small sample, we show that classification with SVM can be considerably enhanced by using a kernel function learned from the training data prior to discrimination. Thi...
Tomer Hertz, Aharon Bar-Hillel, Daphna Weinshall
BMCBI
2010
156views more  BMCBI 2010»
13 years 11 months ago
Comparative classification of species and the study of pathway evolution based on the alignment of metabolic pathways
Background: Pathways provide topical descriptions of cellular circuitry. Comparing analogous pathways reveals intricate insights into individual functional differences among speci...
Adi Mano, Tamir Tuller, Oded Béjà, R...
BMCBI
2007
182views more  BMCBI 2007»
13 years 11 months ago
Identifying regulatory targets of cell cycle transcription factors using gene expression and ChIP-chip data
Background: ChIP-chip data, which indicate binding of transcription factors (TFs) to DNA regions in vivo, are widely used to reconstruct transcriptional regulatory networks. Howev...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen