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» Gene functional classification from heterogeneous data
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BIBM
2008
IEEE
175views Bioinformatics» more  BIBM 2008»
14 years 4 months ago
Integrative Protein Function Transfer Using Factor Graphs and Heterogeneous Data Sources
We propose a novel approach for predicting protein functions of an organism by coupling sequence homology and PPI data between two (or more) species with multifunctional Gene Onto...
Antonina Mitrofanova, Vladimir Pavlovic, Bud Mishr...
BMCBI
2008
167views more  BMCBI 2008»
13 years 10 months ago
Expression profiles of switch-like genes accurately classify tissue and infectious disease phenotypes in model-based classificat
Background: Large-scale compilation of gene expression microarray datasets across diverse biological phenotypes provided a means of gathering a priori knowledge in the form of ide...
Michael Gormley, Aydin Tozeren
MCS
2009
Springer
14 years 4 months ago
Ensemble Based Data Fusion for Gene Function Prediction
The availability of an ever increasing amount of data sources due to recent advances in high throughput biotechnologies opens unprecedented opportunities for genome-wide gene funct...
Matteo Re, Giorgio Valentini
APBC
2004
138views Bioinformatics» more  APBC 2004»
13 years 11 months ago
Whole-Genome Functional Classification of Genes by Latent Semantic Analysis on Microarray Data
Quantitative simultaneous monitoring of the expression levels of thousands of genes under various experimental conditions is now possible using microarray experiments. The resulti...
See-Kiong Ng, Zexuan Zhu, Yew-Soon Ong
BMCBI
2005
169views more  BMCBI 2005»
13 years 9 months ago
Genetic interaction motif finding by expectation maximization - a novel statistical model for inferring gene modules from synthe
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...
Yan Qi 0003, Ping Ye, Joel S. Bader