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    » Gene set analysis for longitudinal gene expression data
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    BMCBI
    2004
    146views more  BMCBI 2004»
    Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
    13 years 8 months ago
    Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
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    Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
    Feng Gao, Barrett C. Foat, Harmen J. Bussemaker
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    BMCBI
    2008
    181views more  BMCBI 2008»
    Assessing batch effects of genotype calling algorithm BRLMM for the Affymetrix GeneChip Human Mapping 500 K array set using 270
    13 years 7 months ago
    Assessing batch effects of genotype calling algorithm BRLMM for the Affymetrix GeneChip Human Mapping 500 K array set using 270
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    Background: Genome-wide association studies (GWAS) aim to identify genetic variants (usually single nucleotide polymorphisms [SNPs]) across the entire human genome that are associ...
    Huixiao Hong, Zhenqiang Su, Weigong Ge, Leming M. ...
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    BIBE
    2007
    IEEE
    108views Bioinformatics» more  BIBE 2007»
    On the Design of Oligos for Gene Synthesis
    14 years 3 months ago
    On the Design of Oligos for Gene Synthesis
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    — Methods for reliable synthesis of long genes offer great promise for protein synthesis via expression of synthetic genes, with applications to improved analysis of protein stru...
    Chris Thachuk, Anne Condon
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    BMCBI
    2008
    98views more  BMCBI 2008»
    Empirical Bayes models for multiple probe type microarrays at the probe level
    13 years 9 months ago
    Empirical Bayes models for multiple probe type microarrays at the probe level
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    Background: When analyzing microarray data a primary objective is often to find differentially expressed genes. With empirical Bayes and penalized t-tests the sample variances are...
    Magnus Åstrand, Petter Mostad, Mats Rudemo
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    BMCBI
    2007
    122views more  BMCBI 2007»
    Dissecting complex transcriptional responses using pathway-level scores based on prior information
    13 years 8 months ago
    Dissecting complex transcriptional responses using pathway-level scores based on prior information
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    Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
    Harmen J. Bussemaker, Lucas D. Ward, André ...
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