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» Gene set analysis for longitudinal gene expression data
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BMCBI
2006
154views more  BMCBI 2006»
13 years 8 months ago
Analysis with respect to instrumental variables for the exploration of microarray data structures
Background: Evaluating the importance of the different sources of variations is essential in microarray data experiments. Complex experimental designs generally include various fa...
Florent Baty, Michaël Facompré, Jan Wi...
BMCBI
2007
139views more  BMCBI 2007»
13 years 8 months ago
Bioinformatics analysis of the early inflammatory response in a rat thermal injury model
Background: Thermal injury is among the most severe forms of trauma and its effects are both local and systemic. Response to thermal injury includes cellular protection mechanisms...
Eric Yang, Timothy Maguire, Martin L. Yarmush, Fra...
TCBB
2008
116views more  TCBB 2008»
13 years 8 months ago
Inferring Connectivity of Genetic Regulatory Networks Using Information-Theoretic Criteria
Recently, the concept of mutual information has been proposed for inferring the structure of genetic regulatory networks from gene expression profiling. After analyzing the limitat...
Wentao Zhao, Erchin Serpedin, Edward R. Dougherty
CSB
2005
IEEE
130views Bioinformatics» more  CSB 2005»
14 years 2 months ago
iSimBioSys: An "In Silico" Discrete Event Simulation Framework for Modeling Biological Systems
The genome projects have provided comprehensive information about the basic building blocks of life. The next challenge is to understand how biological functions emerge from compl...
Samik Ghosh, Preetam Ghosh, Kalyan Basu, Sajal K. ...
TCBB
2008
113views more  TCBB 2008»
13 years 8 months ago
Efficient Algorithms for the Computational Design of Optimal Tiling Arrays
The representation of a genome by oligonucleotide probes is a prerequisite for the analysis of many of its basic properties, such as transcription factor binding sites, chromosomal...
Alexander Schliep, Roland Krause