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» Gene set analysis using principal components
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BIOCOMP
2006
14 years 1 days ago
The Multi-Node Topological Overlap Measure For Gene Neighborhood Analysis
Defining the neighborhood of an initial set of nodes is an important task in network analysis. For example, we show that the neighborhood of an initial set of brain cancer related ...
Ai Li, Steve Horvath
BMCBI
2011
13 years 5 months ago
Investigating the effect of paralogs on microarray gene-set analysis
Background: In order to interpret the results obtained from a microarray experiment, researchers often shift focus from analysis of individual differentially expressed genes to an...
Andre J. Faure, Cathal Seoighe, Nicola J. Mulder
BMCBI
2006
82views more  BMCBI 2006»
13 years 10 months ago
A method for computing the overall statistical significance of a treatment effect among a group of genes
Background: In studies that use DNA arrays to assess changes in gene expression, our goal is to evaluate the statistical significance of treatments on sets of genes. Genes can be ...
Robert R. Delongchamp, Taewon Lee, Cruz Velasco
BMCBI
2007
112views more  BMCBI 2007»
13 years 10 months ago
Selecting dissimilar genes for multi-class classification, an application in cancer subtyping
Background: Gene expression microarray is a powerful technology for genetic profiling diseases and their associated treatments. Such a process involves a key step of biomarker ide...
Zhipeng Cai, Randy Goebel, Mohammad R. Salavatipou...
WSC
2001
14 years 19 hour ago
Dimensionality analysis of a simulation outcome space
This paper investigates the dimensionality characteristics of the outcome space of a combat simulation. The independent state variables of all of the outcome states for a simulati...
John B. Gilmer Jr., Frederick J. Sullivan