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» Gene set analysis using principal components
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153
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BIBM
2008
IEEE
125views Bioinformatics» more  BIBM 2008»
15 years 3 months ago
Systems Biology via Redescription and Ontologies (III): Protein Classification Using Malaria Parasite's Temporal Transcriptomic
This paper addresses the protein classification problem, and explores how its accuracy can be improved by using information from time-course gene expression data. The methods are ...
Antonina Mitrofanova, Samantha Kleinberg, Jane Car...
131
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BMCBI
2004
158views more  BMCBI 2004»
15 years 3 months ago
A novel Mixture Model Method for identification of differentially expressed genes from DNA microarray data
Background: The main goal in analyzing microarray data is to determine the genes that are differentially expressed across two types of tissue samples or samples obtained under two...
Kayvan Najarian, Maryam Zaheri, Ali Ajdari Rad, Si...
BMCBI
2006
103views more  BMCBI 2006»
15 years 3 months ago
Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression
Background: The identification of differentially expressed genes (DEGs) from Affymetrix GeneChips arrays is currently done by first computing expression levels from the low-level ...
Sébastien Lemieux
BMCBI
2005
133views more  BMCBI 2005»
15 years 3 months ago
Ab initio identification of putative human transcription factor binding sites by comparative genomics
Background: Understanding transcriptional regulation of gene expression is one of the greatest challenges of modern molecular biology. A central role in this mechanism is played b...
Davide Corà, Carl Herrmann, Christoph Diete...
INFOVIS
2005
IEEE
15 years 9 months ago
Low-Level Components of Analytic Activity in Information Visualization
Existing system-level taxonomies of visualization tasks are geared more towards the design of particular representations than the facilitation of user analytic activity. We presen...
Robert A. Amar, James Eagan, John T. Stasko