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» Gene-set approach for expression pattern analysis
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BMCBI
2010
153views more  BMCBI 2010»
13 years 6 months ago
DiffCoEx: a simple and sensitive method to find differentially coexpressed gene modules
Background: Large microarray datasets have enabled gene regulation to be studied through coexpression analysis. While numerous methods have been developed for identifying differen...
Bruno M. Tesson, Rainer Breitling, Ritsert C. Jans...
BMCBI
2006
183views more  BMCBI 2006»
13 years 7 months ago
Mining gene expression data by interpreting principal components
Background: There are many methods for analyzing microarray data that group together genes having similar patterns of expression over all conditions tested. However, in many insta...
Joseph C. Roden, Brandon W. King, Diane Trout, Ali...
BMCBI
2007
122views more  BMCBI 2007»
13 years 7 months ago
Dissecting complex transcriptional responses using pathway-level scores based on prior information
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Harmen J. Bussemaker, Lucas D. Ward, André ...
BMCBI
2011
13 years 2 months ago
Investigating the effect of paralogs on microarray gene-set analysis
Background: In order to interpret the results obtained from a microarray experiment, researchers often shift focus from analysis of individual differentially expressed genes to an...
Andre J. Faure, Cathal Seoighe, Nicola J. Mulder
ACAL
2007
Springer
14 years 1 months ago
An Integrated QAP-Based Approach to Visualize Patterns of Gene Expression Similarity
Abstract. This paper illustrates how the Quadratic Assignment Problem (QAP) is used as a mathematical model that helps to produce a visualization of microarray data, based on the r...
Mario Inostroza-Ponta, Alexandre Mendes, Regina Be...