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BMCBI
2006
114views more  BMCBI 2006»
15 years 4 months ago
A methodology for global validation of microarray experiments
Background: DNA microarrays are popular tools for measuring gene expression of biological samples. This ever increasing popularity is ensuring that a large number of microarray st...
Mathieu Miron, Owen Z. Woody, Alexandre Marcil, Ca...
BMCBI
2005
89views more  BMCBI 2005»
15 years 4 months ago
An empirical analysis of training protocols for probabilistic gene finders
Background: Generalized hidden Markov models (GHMMs) appear to be approaching acceptance as a de facto standard for state-of-the-art ab initio gene finding, as evidenced by the re...
William H. Majoros, Steven Salzberg
117
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JCT
2010
83views more  JCT 2010»
15 years 2 months ago
Families of prudent self-avoiding walks
A self-avoiding walk (SAW) on the square lattice is prudent if it never takes a step towards a vertex it has already visited. Prudent walks differ from most classes of SAW that ha...
Mireille Bousquet-Mélou
WABI
2010
Springer
128views Bioinformatics» more  WABI 2010»
15 years 2 months ago
Sparsification of RNA Structure Prediction Including Pseudoknots
Background: Although many RNA molecules contain pseudoknots, computational prediction of pseudoknotted RNA structure is still in its infancy due to high running time and space con...
Mathias Möhl, Raheleh Salari, Sebastian Will,...
BMCBI
2010
137views more  BMCBI 2010»
14 years 11 months ago
The ancient history of the structure of ribonuclease P and the early origins of Archaea
Background: Ribonuclease P is an ancient endonuclease that cleaves precursor tRNA and generally consists of a catalytic RNA subunit (RPR) and one or more proteins (RPPs). It repre...
Feng-Jie Sun, Gustavo Caetano-Anollés