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BMCBI
2008
13 years 11 months ago
2008
Background: Mixture models of mutagenetic trees are evolutionary models that capture several pathways of ordered accumulation of genetic events observed in different subsets of pa...
BMCBI
2008
2008
Modifying the DPClus algorithm for identifying protein complexes based on new topological structures
13 years 11 months ago
Background: Identification of protein complexes is crucial for understanding principles of cellular organization and functions. As the size of protein-protein interaction set incr...
BMCBI
2008
13 years 11 months ago
2008
Background: Analysis of complex samples with tandem mass spectrometry (MS/MS) has become routine in proteomic research. However, validation of database search results creates a bo...
BMCBI
2008
13 years 11 months ago
2008
Background: Protein structure prediction and computational protein design require efficient yet sufficiently accurate descriptions of aqueous solvent. We continue to evaluate the ...
BMCBI
2008
13 years 11 months ago
2008
Background: The principles of protein folding and evolution pose problems of very high inherent complexity. Often these problems are tackled using simplified protein models, e.g. ...