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BIOINFORMATICS
2006
96views more  BIOINFORMATICS 2006»
13 years 11 months ago
Joint estimation of calibration and expression for high-density oligonucleotide arrays
Motivation: The need for normalization in microarray experiments has been well documented in the literature. Currently, most analysis methods treat normalization and analysis as a...
Ann L. Oberg, Douglas W. Mahoney, Karla V. Ballman...
BIOINFORMATICS
2005
61views more  BIOINFORMATICS 2005»
13 years 10 months ago
Identification and measurement of neighbor-dependent nucleotide substitution processes
Abstract: The presence of different neighbor dependent substitution processes generates specific patterns of dinucleotide frequencies in all organisms. Based on a general framework...
Peter F. Arndt, Terence Hwa
BIB
2007
108views more  BIB 2007»
13 years 11 months ago
Bayesian methods in bioinformatics and computational systems biology
Bayesian methods are valuable, inter alia, whenever there is a need to extract information from data that is uncertain or subject to any kind of error or noise (including measurem...
Darren J. Wilkinson
XPU
2007
Springer
14 years 5 months ago
A Case Study of the Implementation of Agile Methods in a Bioinformatics Project
From July 2005 to August 2006, a bioinformatics project experienced a substantial transformation by adopting Scrum and some XP practices. The paper reveals project risks, previous ...
Xueling Shu, Andrei L. Turinsky, Christoph W. Sens...
BMCBI
2010
90views more  BMCBI 2010»
13 years 11 months ago
Local alignment of generalized k-base encoded DNA sequence
Background: DNA sequence comparison is a well-studied problem, in which two DNA sequences are compared using a weighted edit distance. Recent DNA sequencing technologies however o...
Nils Homer, Stanley F. Nelson, Barry Merriman