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BMCBI
2010
132views more  BMCBI 2010»
13 years 7 months ago
Data structures and compression algorithms for high-throughput sequencing technologies
Background: High-throughput sequencing (HTS) technologies play important roles in the life sciences by allowing the rapid parallel sequencing of very large numbers of relatively s...
Kenny Daily, Paul Rigor, Scott Christley, Xiaohui ...
BMCBI
2007
130views more  BMCBI 2007»
13 years 7 months ago
Reproducibility of microarray data: a further analysis of microarray quality control (MAQC) data
Background: Many researchers are concerned with the comparability and reliability of microarray gene expression data. Recent completion of the MicroArray Quality Control (MAQC) pr...
James J. Chen, Huey-miin Hsueh, Robert R. Delongch...
BMCBI
2008
175views more  BMCBI 2008»
13 years 7 months ago
Synonym set extraction from the biomedical literature by lexical pattern discovery
Background: Although there are a large number of thesauri for the biomedical domain many of them lack coverage in terms and their variant forms. Automatic thesaurus construction b...
John McCrae, Nigel Collier
BMCBI
2007
123views more  BMCBI 2007»
13 years 7 months ago
Heritable clustering and pathway discovery in breast cancer integrating epigenetic and phenotypic data
Background: In order to recapitulate tumor progression pathways using epigenetic data, we developed novel clustering and pathway reconstruction algorithms, collectively referred t...
Zailong Wang, Pearlly Yan, Dustin P. Potter, Chari...
BMCBI
2008
117views more  BMCBI 2008»
13 years 7 months ago
CrossHybDetector: detection of cross-hybridization events in DNA microarray experiments
Background: DNA microarrays contain thousands of different probe sequences represented on their surface. These are designed in such a way that potential cross-hybridization reacti...
Paolo Uva, Emanuele de Rinaldis
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